Biography

As a Gates Scholar, I studied for a PhD in the department of Chemistry in the laboratory of Professor Michele Vendruscolo, where I worked on developing computational methods to determine protein structures and conformational ensembles that describe the motions of dynamic proteins. These techniques were utilized investigate the processes of protein folding and misfolding.

After my studies at Cambridge I worked as an NSF postdoctoral in the laboratory of Professor Arthur G. Palmer III at Columbia University, where I studied the role of conformational dynamics in protein function with NMR spectroscopy and molecular simulations.

I then worked as a scientist at D.E. Shaw Research, where I developed new physical models that have enabled the accurate simulation of intrinsically disordered proteins.

As an Assistant Professor of Chemistry and Computational Molecular Science at Dartmouth College, my group utilizes molecular simulations to obtain atomistic descriptions of the molecular recognition mechanisms of intrinsically disordered proteins. We aim to use insights form these simulations to understand, predict and ultimately design dynamic and heterogeneous binding interactions of disordered proteins, with a goal of developing new avenues to therapeutic interventions in diseases associated with disordered protein dysfunction through the rational design of biologic and small molecule inhibitors.

Previous Education

Pomona College BA Chemistry 2006