After transferring from Schreyer Honors College at PSU to University of Pittsburgh for a neuroscience degree, I helped investigate biomarkers for psychosis by processing auditory evoked potentials and brain imaging. I later conducted biochemical research on synaptic protein interaction in learning and memory formation. These experiences prepared me for the data driven, neurochemical nature of my MPhil with Mr. Adel Helmy, inspired by observing surgeries and volunteering on hospital floors with patients being treated for nervous system injuries of varying severity; I questioned the impact of neuroinflammation on outcomes. Insight into neurotrauma is urgent because of the expected increase in its global incidence and it being one of the most abrupt causes of significant disability despite preventability and treatability. My aims are to use data from the largest cerebral microdialysis-monitored cohort to elucidate post-TBI correlations between brain metabolites and outcomes to guide intervention preventing inflammation and deterioration and to progress resource-stratified clinical guidelines for neurotrauma in low- and middle-income countries where there is threefold the incidence of TBI and associated mortality.