Out of the curiosity of cell signalling, I chose biological sciences as my major in Xiamen University and got the admission to the Beutler Institute, where the training of genetics and immunology presented me the promising future of precision medicine as an alternative treatment of infectious diseases. Specific genetic variations among the population can disrupt host immunity and confer vulnerability to certain infectious diseases. Studying genes that participate in immune responses, therefore, enables us to develop novel therapies targeting related pathways and apply them to patients carrying those mutations. In my PhD study, I will focus my research on tuberculosis, a continuous threatening disease for the human being, especially in developing areas. By identifying genes that affect the host susceptibility to mycobacterial infection and revealing their functions in pathogenesis, discoveries will be likely to promote our understanding in the fundamental mechanisms of our immune system, and shed light on host genotype-specific therapies to the tuberculosis infection, which enable patients to receive personalized treatment with lowest cost but highest efficiency. It is a great honour of being one of Gates scholars and joining the community with the shared commitment for benefiting others. I hope my endeavour will contribute to diminishing the inequality of medical treatments around the world.
Xiamen University Biological Sciences 2018